Lipophilic derivatives of chelate monoamides

A - Human Necessities – 61 – B

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A61B 5/055 (2006.01) C07D 225/00 (2006.01)

Patent

CA 2569461

Compounds useful for associating with nanoparticle or microparticle emulsions to obtain magnetic resonance images permit control of the relaxivity of the signal and readily associate with the particulate components. The compounds are conveniently prepared from achiral derivatives of chelating moieties.

La présente invention se rapporte à des composés utiles lorsqu'ils sont associés à des émulsions de nanoparticules ou de microparticules afin de former des images par résonance magnétique. Lesdits composés régulent la relaxivité du signal et s'associent aux éléments particulaires. Les composés peuvent être avantageusement préparés à partir de dérivés achiraux de groupes fonctionnels chélateurs.

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