Liposomal encapsulated nucleic acid-complexes

Details Liposomal encapsulated nucleic acid-complexes Liposomal encapsulated nucleic acid-complexes

C - Chemistry, Metallurgy

12

N

C12N 15/88 (2006.01) A61K 9/127 (2006.01) A61K 48/00 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2335393

This invention relates to liposomes which are useful for the introduction of nucleic acids into cells. The liposomes of the present invention entrap a condensing agent-nucleic acid complex and are suitable for nucleic acid-transfer delivery vehicles in clinical use. In addition, methods of transfecting a cell with a nucleic acid using the liposomes of the present invention are also disclosed.

L'invention concerne des liposomes utiles pour introduire des acides nucléiques dans des cellules. Ces liposomes contiennent un complexe d'acides nucléiques et d'agents de condensation et constituent un support approprié d'administration d'acides nucléiques à des fins cliniques. Elle concerne également des procédés servant à transfecter une cellule par un acide nucléique au moyen de ces liposomes.

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