A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 31/7072 (2006.01) A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2360941
A method for administering a radiosensitizer to a tumor site in a subject is described. The method includes preparing liposomes composed of a vesicle- forming lipid and a lipid-derivatized radiosensitizer. In one embodiment, the radiosensitizer is dipalmitoyl-5-iodo-2'-deoxyuridine. A method for preparing the liposome composition including the lipid-derivatized radiosensitizer is also disclosed.
L'invention concerne un procédé d'admisnistration d'une substance chimique radiosensibilisante dans un foyer de tumeur chez un sujet. Ce procédé consiste à préparer des liposomes composés d'un lipide en forme de vésicule et d'une substance chimique radiosensibilisante dérivée de lipides. Selon un mode de réalisation, la substance chimique radiosensibilisante est la dipalmitoyl-5-iodo-2'-désoxyuridine. Cette invention concerne également un procédé de préparation de ladite composition de liposomes contenant la substance chimique radiosensibilisante dérivée de lipides.
Hjortsvang Kristen M.
Slater James L.
Uster Paul S.
Zetter Adam A.
Zhu George Z.
Alza Corporation
Smart & Biggar
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