C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 263/32 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/445 (2006.01) C07C 229/12 (2006.01) C07D 211/62 (2006.01) C07D 277/24 (2006.01) C07D 295/08 (2006.01) C07D 295/092 (2006.01)
Patent
CA 2282349
The present invention provides compounds having structure (I) and pharmaceutically acceptable salts and stereoisomers thereof that are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as psoriasis, ulcerative colitis, IBD, and asthma.
La présente invention concerne des composés présentant la structure (I), des sels pharmaceutiquement acceptables et des stéréoisomères de ces composés, qui sont utilisés dans le traitement de maladies inflammatoires qui sont médiées par la production de LTB¿4?, telles que le psoriasis, la rectocolite hémorragique, la maladie intestinale inflammatoire et l'asthme.
Chen Barbara B.
Chen Helen
Malecha James W.
Miyashiro Julie M.
Penning Thomas D.
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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