Lxr receptor modulators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 209/42 (2006.01) A61K 31/404 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07D 215/58 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2564642

The invention relates to compounds which are derived from benzenesulfonamide of general formula (I) as described in the claims, and to the pharmaceutically acceptable addition salts thereof. The invention also relates to a method for the preparation thereof, pharmaceutical compositions containing them, and to the use thereof as a pharmacologically active substance in the treatment of neurodegeneracy, cardiovascular and inflammatory disease, hypecholesterolemia and diabetes.

L'invention concerne des composés dérivés de benzènesulfonamide de formule générale (I) telle que définie dans les revendications, et leurs sels d'addition pharmaceutiquement acceptables. Elle concerne également leur procédé de préparation, les compositions pharmaceutiques les contenant, et leur utilisation en tant que substance pharmacologiquement active, notamment dans le traitement des neurodégénérescences, des maladies cardiovasculaires, inflammatoires, des hypercholestérolémies et du diabète.

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