Lysosomal enzyme-cleavable antitumor drug conjugates

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 47/48 (2006.01) C07K 1/107 (2006.01) C07K 5/02 (2006.01) C07K 5/04 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/087 (2006.01) C07K 7/04 (2006.01) C07K 9/00 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2123363

The present invention relates to drug-ligand conjugates wherein the drug is linked to the ligand through a protein peptide linker and a connector, a process for the preparation of said conjugates, method of controlling the growth of undesirable cells, pharmaceutical compositions, and intermediates thereof.

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