Macrocin derivatives and process for their preparation

Details Macrocin derivatives and process for their preparation Macrocin derivatives and process for their preparation

C - Chemistry, Metallurgy

12

P

195/101, 260/230

C12P 19/62 (2006.01) C07H 17/08 (2006.01)

Patent

CA 1221652

X-5735 Abstract of the Invention New macrocin and lactenocin ester derivatives of the formula: Image wherein R is formyl or hydroxymethyl; R1 is hydrogen, acetyl or propionyl; R2 is hydrogen or Image and R3 is hydrogen, acetyl, propionyl, n-butyryl or isovaleryl; provided that one of R1 or R3 must be other than hydrogen; and the acid addition salts thereof; prepared by bioconversion of macrocin or lactenocin with an acylating enzyme system produced by Strepto- myces thermotolerans strains, have improved activity against Mycoplasma species.

448636

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