Macrocyclic compounds

Details Macrocyclic compounds Macrocyclic compounds

C - Chemistry, Metallurgy

07

H

167/185, 260/228

C07H 17/08 (2006.01) C07H 19/01 (2006.01)

Patent

CA 2023485

ABSTRACT MACROCYCLIC COMPOUNDS There are described compounds of formula I, Image I wherein R1 represents H or OH; R2 represents H; in addition, R1 and R2 may together represent a second carbon-carbon bond between the carbon atoms to which they are attached; R3 represents OH or OCH3; X represents O or (H,OH); and Y represents O or N-OR4, in which R4 represents H or alkyl C1-6; provided that when R1 is OH, R2 is H and X is O, then Y does not represent O. Processes for their production and compositions containing them, eg for use as immunosuppressive agents, are also described.

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