Macrocyclic ns3-serine protease inhibitors of hepatitis c...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/06 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61P 31/14 (2006.01) C07K 1/02 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/08 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/107 (2006.01) C07K 7/02 (2006.01) C07K 14/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2405521

The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.

L'invention porte sur de nouveaux composés macrocycliques présentant une activité inhibitrice de la protéase du VHC et sur ses procédés de préparation. L'invention porte également sur des préparations pharmaceutique comprenant lesdits macrocycles et sur des procédés les utilisant pour traiter des troubles associés à ladite protéase.

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