C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/08 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2432429
The present invention relates to 11,12 .gamma. lactone ketolides of formula (I) wherein R, R1~, R2~, R3~ are as defined herein and pharmaceutically acceptable salts and solvates thereof, to process for their preparation and their use in therapy or prophylaxis of systemic or topical bacterial infections in a human or animal body.
La présente invention concerne des 11,12 gamma lactone kétolides représentés par la formule (I), dans laquelle R, R<1>, R<2> et R<3> sont tels que définis dans la description, ainsi que des sels et des solvates pharmaceutiquement acceptables desdits composés, leur procédé de préparation et leur utilisation dans le traitement ou la prévention d'infections bactériennes topiques ou systémiques chez un humain ou un animal.
Alihodzic Sulejman
Andreotti Daniele
Arista Luca
Biondi Stefano
Cardullo Francesca
Glaxo Group Limited
Gowling Lafleur Henderson Llp
Pliva D.d.
Pliva-Istrazivacki Institut D.o.o.
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