Macrolide antibiotics and treatment of pasteurellosis

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2391834

20,23-disubstituted mycaminosyltylonolide derivatives and use of the same in the field of the prophylaxis and treatment of pasteurellosis are disclosed. The di-sub-stituents are peperidino optionally substituted with one or two methyl groups. The derivatives have selective antibacterial activity against Pasteurella. Image

L'invention concerne des dérivés de mycaminosyltylonolide à disubstitution 20,23, et leur utilisation pour la prophylaxie et le traitement de la pasteurellose. Les disubstituants sont à substitution éventuelle pépéridino par un ou deux groupes méthyle. Les dérivés considérés ont une activité antibactérienne sélective vis-à-vis de la <u>Pasteurella</u>.

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