Macrolide compounds

Details Macrolide compounds Macrolide compounds

C - Chemistry, Metallurgy

12

P

167/202, 260/227

C12P 17/18 (2006.01) A01N 43/32 (2006.01) A01N 43/90 (2006.01) A61K 31/365 (2006.01) C07D 493/22 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1318628

ABSTRACT MACROLIDE COMPOUNDS Compounds of formula (1) (1) Image and their salts, wherein R1 is a methyl, ethyl or isopropyl group each substituted by a hydroxyl group or R1 is a group -(CH2)nR7 or a group -CH(CH3)R7 (where n is zero or 1 and R7 is CHO or CO2H); Y1 is -CH2-,Y2 is -CH- and X represents Image [where R2 is a hydrogen atom or a group OR8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R3 is a hydrogen atom, or R2 and R3 together with the carbon atom to which they are attached represent >C=O, >C=CH2 or >C=NOR9 (where R9 is a hydrogen atom or a C1-8 alkyl or C3-8 alkenyl group) and the group >C=NOR9 is in the E configuration] or -Y1-X-Y2- represents -CH=CH-CH- or -CH2-CH=C-; R4 is a group OR8 as defined above and R5 is a hydrogen atom, or R4 and R5 together with the carbon atom to which they are attached represent >C=O or >C=NOR8a (where R9a is as defined above for R9); and R8 is a hydrogen atom or a hydroxyl group. The compounds may be used to control nematode, acarine, insect or other pests.

601669

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