Macromolecular arrays on polymeric brushes and methods for...

C - Chemistry – Metallurgy – 08 – F

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C08F 20/28 (2006.01) C07H 21/00 (2006.01) C07K 1/04 (2006.01) C08F 4/02 (2006.01) C08F 18/08 (2006.01) C08F 20/26 (2006.01) C08F 263/04 (2006.01) C08F 265/04 (2006.01) C08F 289/00 (2006.01) C08F 290/06 (2006.01) C08L 51/08 (2006.01) C08L 51/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/544 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2317179

Polymeric brush substrates and methods for their preparation are provided. Methods are also provided for preparing macromolecular arrays on such polymeric brush substrates. Using polymeric brush substrates allows control over functional site density as well as wettability and porosity of the substrate. These polymeric brushes are useful in solid-phase synthesis of arrays of peptides, polynucleotides or small organic molecules.

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