C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/72 (2006.01)
Patent
CA 2276921
A process for the manufacture of d,l-.alpha.-tocopherol by the acid- catalyzed condensation of trimethylhydroquinone with isophytol or phytol in ethylene or propylene carbonate or a mixture of both carbonates, or in a mixture of one or both of the carbonates and a non-polar solvent, comprises carrying out the condensation in the presence of at most 0.4 weight percent based on the weight of isophytol or phytol of 12-tungstophosphoric acid, 12- molybdophosphoric acid or 12-tungstosilicic acid. The product of the process is the most active and industrially important member of the vitamin E group.
Aquino Fabrice
Bonrath Werner
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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