Manufacture of d,1-alpha-tocopherol

C - Chemistry – Metallurgy – 07 – D

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C07D 311/72 (2006.01)

Patent

CA 2276921

A process for the manufacture of d,l-.alpha.-tocopherol by the acid- catalyzed condensation of trimethylhydroquinone with isophytol or phytol in ethylene or propylene carbonate or a mixture of both carbonates, or in a mixture of one or both of the carbonates and a non-polar solvent, comprises carrying out the condensation in the presence of at most 0.4 weight percent based on the weight of isophytol or phytol of 12-tungstophosphoric acid, 12- molybdophosphoric acid or 12-tungstosilicic acid. The product of the process is the most active and industrially important member of the vitamin E group.

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