Measles subunit vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/165 (2006.01) A61K 39/39 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2538887

Compositions and methods for making and using therapeutic formulations of measles virus antigens with a Proteosome-based adjuvant are provided. The measles virus antigens may be derived from a variety of sources, such as from recombinant production or from a split antigen preparation. The measles vaccine formulations may be used, for example, in methods for treating or preventing a measles virus infection and eliciting a protective immune response.

L'invention concerne des compositions et des méthodes de fabrication et d'utilisation de préparations thérapeutiques d'antigènes du virus de la rougeole avec un adjuvant à base de protéosomes. Les antigènes du virus de la rougeole peuvent être dérivés de plusieurs sources, par production recombinée ou à partir d'une préparation d'antigène sous-unitaire, par exemple, Ces préparations vaccinales antirougeoleuses peuvent être utilisées, notamment, dans des méthodes de traitement ou de prévention d'une infection par le virus de la rougeole et pour déclencher une réponse immunitaire protectrice.

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