Medicament for treating cerebral insufficiency diseases...

Details Medicament for treating cerebral insufficiency diseases... Medicament for treating cerebral insufficiency diseases...

C - Chemistry, Metallurgy

07

D

167/222, 260/252

C07D 239/70 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2010477

- 50 - Abstracts of the Disclosure: Medicament for the treatment of cerebral insufficiency diseases comprising as an active ingredient a compound of the formula: Image (I) wherein n is 3, 4, 5 or 6; R1 is hydrogen atom, C1-C6 alkyl, C3-C8 cycloalkyl, hydroxy-(C2-C6) alkyl, unsubstituted or substituted aryl, heteroaryl, unsubstituted or substituted aryl-(C1-C6) alkyl, unsubstituted or substituted aryl- carbonyl-(C1-C6) alkyl, or acyl; R2 is hydrogen atom, halogen atom, C1-C6 alkyl, C1-C6 alkoxy, or trifluoromethyl; and R3 is hydrogen atom or C1-C6 alkyl, or an acid addition salt thereof, novel 2-(1-piperazinyl)-4-phenyl-cycloalkano- pyrimidine derivatives having excellent cerebral function improving activity, processes for the preparation thereof.

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