C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/21 (2006.01) A61K 39/095 (2006.01) A61K 39/116 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C07K 14/22 (2006.01)
Patent
CA 2726465
The present technology provides vaccine compositions comprising native outer membrane vesicles (NOMVs) from at least one genetically modified strain of Neisseria which provides protective immunity to meningococcal disease, more preferably subtype B meningococcal disease. The present technology further provides methods of immunizing an animal or human against meningococcal disease comprising administering the vaccine composition of the present invention.
La présente technologie concerne des compositions de vaccin comprenant des vésicules de membrane externe native (NOMV) d'au moins une souche de Neisseria génétiquement modifiée qui fournit une immunité de protection contre une maladie à méningocoques, de préférence une maladie à méningocoques de sous type B. La présente technologie concerne aussi les procédés d'immunisation d'un animal ou d'une personne contre une maladie à méningocoques qui consiste à administrer la composition de vaccin de la présente invention.
Donets Mikhail
Ionin Boris
Marques Ryan
Moran Elizabeth Ellen
Schmiel Deborah
Goudreau Gage Dubuc
On Behalf Of Wa Lter Reed Army The U.s.a. As Represented By The Secretary Of The Army
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