Mercaptoamides as histone deacetylase inhibitors

Details Mercaptoamides as histone deacetylase inhibitors Mercaptoamides as histone deacetylase inhibitors

C - Chemistry, Metallurgy

07

C

C07C 327/06 (2006.01) C07C 323/25 (2006.01) C07D 209/16 (2006.01) C07D 213/40 (2006.01) C07D 213/74 (2006.01) C07D 249/08 (2006.01) C07D 263/32 (2006.01) C07D 263/48 (2006.01) C07D 277/46 (2006.01) C07D 307/52 (2006.01) C07D 307/79 (2006.01) C07D 309/12 (2006.01) C07D 319/18 (2006.01) C07D 333/20 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2579004

Mercaptoamide compounds, represented by Formulas (IA), (IB), (IIA), and (IIB): or a pharmaceutically acceptable salt thereof, inhibit histone deacetylase enzyme and are useful for the treatment and/or prevention of various infections, cancerous diseases, and conditions.

L'invention concerne des composés mercaptoamides représentés par les formules (IA), (IB), (IIA), et (IIB), ou un sel pharmaceutiquement acceptable de ceux-ci. Ces composés inhibent l'enzyme d'histone déacétylase et sont utiles dans le traitement et/ou la prévention de diverses infections, maladies cancéreuses et états pathologiques.

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