Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides

Details Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides

C - Chemistry, Metallurgy

07

D

167/103, 260/284

C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 211/60 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01)

Patent

CA 1269496

HA326 ABSTRACT MERCAPTOCYCLOALXYLCARBONYL AND MERCAPTOARYLCARBONYL DIPEPTIDES Compounds of the formula Image wherein A is a cycloalkyl ring, a substituted cycloalkyl ring, a phenyl ring, or a substituted phenyl ring and Image are various dipeptide groups are disclosed. The compounds possess angiotensin converting enzyme inhibition activity and depending upon the terminal amino acid may also possess enkephalinase inhibition activity.

482355

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