Metal chelate forming peptides and use thereof

Details Metal chelate forming peptides and use thereof Metal chelate forming peptides and use thereof

C - Chemistry, Metallurgy

07

K

C07K 5/08 (2006.01) A61K 51/08 (2006.01) C07K 1/13 (2006.01) C07K 5/087 (2006.01) C07K 5/09 (2006.01) C07K 5/093 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2165228

The invention provides a metal chelate forming peptide having an amino acid sequence of three amino acid residues represented by: X1-X2-Cys, wherein X1 represents an amino acid residue other than Cys residue; X2 represents an amino acid residue other than Cys residue and Pro residue; functional groups at the N-terminus, C-terminus and side chain may be substituted with protecting groups; and each of the amino acid residues may be any of D-form and L-form. Further, the invention provides a complex of the peptide with a physiologically active peptide, protein or other substance; a labeled reagent obtained by labeling the peptide or the complex with a metal radionuclide; and a radiodiagnostic and radiotherapeutic composition compris- ing the metal radionuclide-labeled reagent.

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