Method and agents for promoting wound healing

Details Method and agents for promoting wound healing Method and agents for promoting wound healing

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/19 (2006.01) C07K 16/24 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2103676

2103676 9213553 PCTABS00014 The present invention relates to the treatment of wound healing dysfunction by the administration of one or more wound healing modulators. The wound healing modulator may be selected from appropriate wound healing agents and binding partners, and particularly agents that enhance wound healing. The agent may comprise a cytokine, or mixture of cytokines that are also capable of binding to heparin, and inducing localized inflammation characterized by polymorphonuclear cell infiltration when administered subcutaneously. Particular agents comprise the inflammatory cytokines MIP-1, MIP-1.alpha., MIP-1.beta. and MIP-2. Diagnostic and therapeutic utilities are proposed, and pharmaceutical compositions are likewise set forth.

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