A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01)
Patent
CA 2761678
A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.
La présente invention concerne un comprimé dont le principe médicalement actif tel que l'aspirine a un profil de dissolution amélioré, et des procédés de fabrication du comprimé. Le comprimé comprend un mélange de cristaux du principe médicalement actif et un additif de dissolution comme le carbonate de sodium ou de calcium qui enrobe les cristaux au moment du co-broyage. Le mélange est alors comprimé pour former des comprimés dont le principe médicalement actif a un profil de dissolution amélioré.
First Eric R.
Patel Ashish B.
Petaway-Hickson Stephanie
Schmitz Guido
Tong Hung-Huar
Bayer Healthcare Llc
Fetherstonhaugh & Co.
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