Method and compounds for reducing dermal inflammations

C - Chemistry – Metallurgy – 07 – C

Patent

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167/252, 167/258

C07C 323/59 (2006.01) A61K 31/195 (2006.01) A61K 7/48 (1990.01)

Patent

CA 1333179

Dermal inflammations which are induced and propagated by leukotrienes are treated by topically applying to the inflamed dermis the following compound: Image wherein R3 is H or a thiol; n is 1 to 12; p is 0 to 12; X is a substituted carbonyl, such as an ester or a carboxylic acid; and Y is an aliphatic or branched hydrocarbon, aromatic ring, carbonyl or substituted amide.

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