Method and device for chemical or biological analysis by a...

B - Operations – Transporting – 01 – L

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B01L 3/00 (2006.01) C12M 1/34 (2006.01) C12M 3/06 (2006.01)

Patent

CA 2531237

The invention relates to a method and device for chemical or biological analysis by a sensor provided with a monolithic chamber in the form of a multi-microtubular sheaf and a lateral integration measuring transducer. The aim of said invention is to improve an usual method for a sensor evaluation of an analyte (A) concentration in a fluid sample (F) consisting in multi-canalising in parallel the fluid sample (f) fraction through channels (c¿k?) of a monolithic reaction chamber (Cre) embodied in the form of a multi-micro-tubular sheaf, in positioning a transducer (T) system fully outside the surface of the shell (Sev) of said reaction chamber and strictly in front of the lateral face (slat) thereof, in carrying out an integral measurement of signals generated by the analyte (A) combination and a receiver (R), which is also arranged in the reaction chamber, by means of a lateral transducer (T) system coevally in all channels (c¿k?) of the reaction chamber (Cre) in such a way that the presence of the analyte (A) in all channels (c¿k?) of the reaction chamber (Cre) is simultaneously and globally quantified.

Procédé et dispositif d'analyse chimique ou biologique par senseur à chambre monolithique en gerbe multi-micro-tubulaire et transducteur latéral de mesure intégrale. L'invention propose une amélioration au procédé habituel d'évaluation par senseur de la concentration d'un analyte (A) présent dans un fluide ~échantillon (F) caractéristique par ce qu'en combinaison : d'une part, on multi-canalise en parallèle une fraction du fluide ~échantillon (F) à travers les canaux (ck) d'une chambre de réaction (Cre) monolithique en gerbe multi-micro-tubulaire, d'autre part, on positionne le système transducteur (T) entièrement à l'extérieur de la surface enveloppe (Sev) de la chambre de réaction, et strictement en regard de sa face latérale (slat), et enfin, on effectue grâce au système transducteur latéral (T), concomitamment dans tous les canaux (ck) de la chambre de réaction (Cre), une mesure intégrale des signaux générés par la combinaison de l'analyte (A) et d'un récepteur (R) également présent dans la chambre de réaction. En sorte qu'on quantifie globalement la présence de l'analyte (A) dans tous les canaux micro-tubulaires (ck) de la chambre de réaction (Cre) à la fois.

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