Method and device for forming particles

B - Operations – Transporting – 01 – J

Patent

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Details

B01J 2/04 (2006.01) A61K 9/16 (2006.01) B01F 5/06 (2006.01) B01J 3/00 (2006.01) B01J 19/26 (2006.01)

Patent

CA 2368087

The present invention relates to a method for forming particles of a substance, comprising the step of introducting into a mixing chamber (8), in which the temperature and pressure are controlled, a fluid gas (4) and at least one vehicle system (1) comprising at least one substance in solution or suspension such that droplet formation and extraction of the vehicle occur substantially simultaneously by the action of the fluid gas (4). Turbulence is induced in at least one of said fluid gas (4) and said vehicle system (1) so as to create a controlled disorder in the flow of the at least one of the fluid gas (4) or the vehicle system (1) in order to control the particle formation in said mixing chamber (8), said controlled disorder being created by at least one flow perturbation means (11). The invention also relates to a mixing chamber having at least one flow perturbation means (11) that is disposed for interacting with at least one of a fluid gas (4) or vehicle system (1) supplied by the at least one supply member (4, 5) so as to induce turbulence or limited disorder in the at least one of the fluid gas (4) or vehicle system (1).

La présente invention concerne un procédé pour former des particules d'une substance. Ce procédé comprend l'étape consistant à introduire dans une chambre de mélange (8) dans laquelle la température et la pression sont contrôlées, un gaz fluide (4) et au moins un système de véhicule (1) comprenant au moins une substance en solution ou suspension, de telle sorte que la formation de gouttelettes et l'extraction du véhicule se produisent sensiblement en même temps sous l'action du gaz fluide (4). Une turbulence est induite dans au moins un élément parmi ledit gaz fluide (4) et ledit système de véhicule (1) de manière à créer un trouble contrôlé dans l'écoulement d'au moins un élément parmi le gaz fluide (4) ou le système de véhicule (1) afin de commander la formation de particules dans ladite chambre de mélange (8). Ledit trouble contrôlé est créé par au moins un moyen de perturbation du flux (11). L'invention concerne également une chambre de mélange comportant au moins un moyen de perturbation du flux (11) qui est prévu pour agir avec au moins un élément parmi un gaz fluide (4) ou un système de véhicule (1) fourni par au moins un élément d'alimentation (4, 5) pour induire une turbulence ou un trouble limité dans au moins le gaz fluide (4) ou le système de véhicule (1).

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