C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2651376
The present invention relates to association of one or more polymorphisms located in the human NHP2L1 , PACSIN2, SERHL, PIPPIN, BRD1 , EP300, FAM19A5 and/or GPR24 genes to the occurrence of schizophrenia and/or bipolar disorder. The invention relates both to methods for diagnosing a predisposition to said diseases and for treating subjects having said diseases.
La présente invention concerne l'association d'un ou plusieurs polymorphismes situés dans les gènes humains NHP2L1, PACSIN2, SERHL, PIPPIN, BRD1, EP300, FAM19A5 et/ou GPR24 à l'apparition de la schizophrénie et/ou d'un trouble bipolaire. L'invention porte également sur des méthodes de diagnostic d'une prédisposition à ces maladies et sur des méthodes de traitement de sujets affectés par ces maladies.
Blackwood Douglas
Borglum Anders
Ewald Henrik
Mors Ole
Muir Walter
Aarhus Universitet
Macpherson Leslie & Tyerman Llp
Region Midtjylland
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