Method for predicting the sensitivity to chemotherapy

G - Physics – 01 – N

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G01N 33/574 (2006.01)

Patent

CA 2459194

Herewith described is a novel method for predicting the sensitivity towards chemotherapy, of a patient in need thereof, which comprises obtaining a blood sample from the patient and detecting the levels of blood glutathione (GSH) as a surrogate marker for glutathione-S-transferase (GST) activity in tumor tissues.

L'invention porte sur un nouveau procédé destiné à prévenir la sensibilité à la chimiothérapie chez un patient nécessitant ce traitement. Le procédé consiste à prélever chez ce patient un échantillon de sang et à détecter les taux de glutathion dans le sang (GSH) utile comme marqueur de substitution dans l'activité de glutathion-S-transférase (GST) dans les tissus tumoraux.

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