Method for preparing an aza-macrolide with 4"(r)nh2

Details Method for preparing an aza-macrolide with 4"(r)nh2 Method for preparing an aza-macrolide with 4"(r)nh2

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2359967

The subject-matter of the invention is a process for the stereoselective preparation of a compound of general formula I (see formula I) by stereoselective displacement by a nitrogenous nucleophilic compound of the activated alcohol functional group present at this 4" position in a corresponding derivative of formula II.

L'invention a pour objet un procédé de préparation stéréosélectif d'un composé de formule générale (I) par déplacement stéréosélectif par un nucléophile azoté de la fonction alcool activée en position 4" d'un dérivé de formule générale (II) correspondant.

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