Method for producing camptothecin derivatives

Details Method for producing camptothecin derivatives Method for producing camptothecin derivatives

C - Chemistry, Metallurgy

07

D

C07D 491/22 (2006.01) B01J 23/755 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2725560

The invention offers a method of hydrogenating camptothecin in inert solvent in the presence of nickel catalyst, whereby selective hydrogenation of camptothecin can be very efficiently accomplished using the low-cost catalyst.

La présente invention concerne un procédé permettant d'hydrogéner la camptothécine en présence d'un catalyseur au nickel dans un solvant non réactif. Ce procédé permet une hydrogénation sélective efficace de la camptothécine au moyen d'un catalyseur bon marché.

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