Method for producing carboxy-terminal amidified peptides

C - Chemistry – Metallurgy – 12 – N

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C12N 15/16 (2006.01) A61K 38/00 (2006.01) A61K 38/22 (2006.01) A61K 38/26 (2006.01) A61P 3/10 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/575 (2006.01) C07K 14/605 (2006.01) C12N 15/11 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2589951

The invention relates to the production of carboxy-terminal (C-terminal) amidified peptides with C-terminal amidified lysin, in particular with the biological activity of GLP-1, the chemical and/or biotechnological precursors and intermediate products thereof. The invention also relates to a method for the production and use thereof for producing pharmaceutical products.

La présente invention concerne la production de peptides à amidification carboxy-terminale (C-terminale) avec une lysine à amidification C-terminale, en particulier avec l'activité biologique du GLP-1, leurs produits intermédiaires et précurseurs chimiques et biotechnologiques, un procédé de production desdits peptides et leurs utilisations dans l'élaboration de produits pharmaceutiques.

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