Method for production of solid pharmaceutical preparation

Details Method for production of solid pharmaceutical preparation Method for production of solid pharmaceutical preparation

A - Human Necessities

61

K

A61K 9/32 (2006.01) A61J 3/06 (2006.01) A61K 9/00 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2100272

2100272 9211845 PCTABS00014 The invention provides a method for the production of a solid pharmaceutical preparation characterised by mixing together finely divided particles or granules of a medicament, or granules containing a medicament and excipients, and appropriate amounts of a finely divided amorphous or substantially amorphous coating polymer and plasticizer which dissolves the polymer, compressing the mixture into tablets, and heating the tablets to a temperature at which fusion of the polymer particles occurs; and a method for the production of a solid pharmaceutical preparation characterised in that a solid core is coated with a film coat by mixing or granulating finely divided particles of a membrane-forming amorphous or substantially amorphous polymer with a plasticizer which dissolves the polymer, encasing said solid core with the polymer mix, and heating the polymer-encased material to a temperature at which the amorphous or substantially amorphous polymer forms a continuous film.

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