Method for reducing chemical background in mass spectra

Details Method for reducing chemical background in mass spectra Method for reducing chemical background in mass spectra

G - Physics

01

N

G01N 27/00 (2006.01) G01D 3/028 (2006.01) H01J 49/04 (2006.01) H01J 49/26 (2006.01)

Patent

CA 2307399

A computer-based method for reducing chemical background in acquired electrospray and nanospray mass spectra, which comprises the steps of pre-processing an acquired mass spectrum, transforming the pre-processed mass spectrum into the frequency domain, reducing peaks in the transformed mass spectrum at calculated frequencies, applying an inverse transformation to the mass spectrum represented in the frequency domain, further processing and subsequent output of a mass spectrum with chemical background reduced. The invention enables rapid, automated generation of mass spectra with the component attributed to chemical background reduced, thereby allowing the mass spectrum to be analyzed more easily and effectively. The invention also generates mass spectra with improved signal-to-noise ratio and sample mass accuracy.

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