A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/14 (2006.01) A61F 2/44 (2006.01) A61K 31/66 (2006.01) A61K 31/722 (2006.01) A61K 31/728 (2006.01) A61K 31/737 (2006.01) A61K 31/765 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2429168
The present invention relates to a minimally-invasive method for restoring a damaged or degenerated intervertebral disc at an early stage. The method comprises the step of administering an injectable in situ setting formulation in the nucleus pulposus of the damaged or degenerated disc of a patient. The formulation once injected combines with nucleus matters and host cells, and becomes viscous or gels in situ within the annulus fibrosus of the disc for increasing the thickness and volume of the damaged or degenerated disc. The formulation is retained within the disc for providing restoration of the damaged or degenerated disc.
La présente invention porte sur un procédé de restauration avec effraction minimale d'un disque intervertébral endommagé ou atteint de dégénérescence à un stade précoce. Le procédé consiste à administrer une formulation de solidification injectable in situ dans le noyau gélatineux du disque. Une fois injectée, la formulation se combine à des substances du noyau et des cellules hôtes et devient visqueuse ou prend l'apparence de gels in situ dans l'anneau fibreux du disque de façon à augmenter l'épaisseur et le volume du disque endommagé ou atteint de dégénérescence. La formulation est retenue dans le disque pour assurer la restauration de celui-ci.
Berrada Mohammed
Chaput Cyril
Chenite Abdellatif
Desrosiers Eric Andre
Bio Syntech Canada Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Piramal Healthcare (canada) Limited
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