C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/139, 195/1.1
C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2020593
ABSTRACT OF THE DISCLOSURE It has been found that monoclonal antibodies which specifically bind to the protein portion of the 80 kilodalton glycoprotein receptor for bacterial lipopolysaccharide endotoxin, 5D3 in particular, stimulate the cytotoxic effect of macrophages against tumors, such as plasmocytomas. The effect is potentiated by combination with gamma interferon. Also described are compositions containing the monoclonal antibody and gamma interferon.
Bright Stuart W.
Chen Taiying
Flebbe Linda M.
Lei Mei-Guey
Morrison David C.
Bright Stuart W.
Chen Taiying
Flebbe Linda M.
Lei Mei-Guey
Morrison David C.
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