C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) G06F 19/00 (2006.01)
Patent
CA 2551796
Method for the humanization of the VH and VL variable regions of an animal antibody of known sequence, humanized animal antibody obtainable according to the method, in particular anti-NGF and anti-TrkA humanized animal antibodies.
La présente invention porte sur un procédé d'humanisation des régions VH et VL variables d'un anticorps animal de séquence connue, sur l'anticorps animal humanisé obtenu selon ledit procédé, en particulier sur des anticorps animaux humanisés anti-NGF et anti-TrkA.
Cattaneo Antonino
Covaceuszach Sonia
Lamba Doriano
Dennison Associates
Lay Line Genomics S.p.a.
Scuola Internazionale Superiore Di Studi Avanzati-Sissa
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