Method for the preparation of a pharmaceutically usable...

Details Method for the preparation of a pharmaceutically usable... Method for the preparation of a pharmaceutically usable...

C - Chemistry, Metallurgy

07

D

260/243.21

C07D 279/02 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1246066

ABSTRACT This invention relates to a method for the preparation of a pharmaceutically usable 2-methyl-4-hydroxy-2H-1,2-benzothiazine- 1,1-dioxide with formula I Image I In accordance with the invention 2-methyl-4-mesyloxy-2H,1,2- benzothiazine-1,1-dioxide-3-carboxylic acid with formula II Image II is reacted with 2-aminopyridine in the presence of thionyl chloride in an inert solvent. The invention relates also to the intermediate with formula II which can be used in the method.

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