Method for the stabilization of proteins and the...

Details Method for the stabilization of proteins and the... Method for the stabilization of proteins and the...

C - Chemistry, Metallurgy

12

N

C12N 15/53 (2006.01) C12N 1/21 (2006.01) C12N 9/04 (2006.01)

Patent

CA 2290074

The present invention provides a method for the directed evolution of proteins, particularly a method for improving the thermostability of proteins, particularly alcohol dehydrogenases, and especially horse liver alcohol dehydrogenase. The present invention also provides thermostabilized alcohol dehydrogenases produced according to this method.

La présente invention concerne un procédé permettant l'évolution dirigée de protéines, en particulier un procédé permettant d'améliorer la thermostabilité de protéines, en particulier d'alcool-déshydrogénases et notamment d'alcool-déshydrogénases de foie de cheval. La présente invention concerne également les alcool-déshydrogénases thermostabilisées produites selon ce procédé.

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