A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2575309
Processes for coating implantable medical devices that improve the stability of therapeutic agents contained within the coating. In one embodiment, the process comprises: applying a primer coating on the implantable medical device; preparing a basecoat solution comprising polymers and a therapeutic agent and applying the basecoat solution to the implantable medical devices; preparing a topcoat solution comprising at least one polymer and applying the topcoat solution to the implantable medical devices coated with the basecoat solution; applying a solvent to partially redissolve the topcoat and basecoat while altering the surface finish and dissolution properties of the therapeutic agent; and final processing the implantable medical devices, including inspecting, packaging and sterilizing the coated medical devices.
L'invention concerne des procédés destinés à revêtir des dispositifs médicaux implantables et permettant d'améliorer la stabilité d'agents thérapeutiques contenus dans le revêtement.
Akerman Eugena A.
Cleeren Dirk
Llanos Gerard
Maryanoff Cynthia A.
Papandreou Georgios
Cordis Corporation
Sim & Mcburney
LandOfFree
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