Method of detecting mutations associated with thrombosis

Details Method of detecting mutations associated with thrombosis Method of detecting mutations associated with thrombosis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2546171

The present invention provides a method for the simultaneous identification of two or more single base changes in a plurality of target nucleotide sequences that are markers associated with cardiovascular diseases such as deep vein thrombosis and the like. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.

Cette invention se rapporte à un procédé servant à identifier simultanément deux changements de simple base ou davantage dans plusieurs séquences nucléotidiques cibles qui constituent des marqueurs associés à une maladie cardio-vasculaire telle que la thrombose veineuse profonde et similaire. On effectue à cet effet une détection multiplex en utilisant une extension d'amorces spécifiques d'allèles marqués multiplexés (ASPE) et l'hybridation des amorces ainsi étendues à une sonde, telle que de préférence un support non marqué adressable.

Affiliated with

Also associated with

Rating

Method of detecting mutations associated with thrombosis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of detecting mutations associated with thrombosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detecting mutations associated with thrombosis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1884447