Method of making liposomes with improved stability during...

Details Method of making liposomes with improved stability during... Method of making liposomes with improved stability during...

A - Human Necessities

61

K

167/163

A61K 9/127 (2006.01) A61K 47/26 (2006.01) A61K 47/42 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2000219

Abstract A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave biologically in a normal fashion. The cryoprotective agents are used in the aqueous medium to hydrate the phospholipid(s) and are a combination of at least one sugar and at least one protein, polypeptide, and/or oligopeptide.

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