Method of suppressing appetite by administration of...

Details Method of suppressing appetite by administration of... Method of suppressing appetite by administration of...

A - Human Necessities

61

K

A61K 31/44 (2006.01)

Patent

CA 2058771

Compounds of formula I are useful for suppressing appetite, and for altering macronutrient preferences, Image (I) wherein R2, R3, R6, R7, and R9 are chosen such that the predicted activity, measured in terms of IC50, as calculated by the quantitative structure activity relationship 1n(1/IC50) = 0.058P2 + 0.908(? + .sigma.I) - 2.647 is greater than about -2.5, where P is the octanol/water partition coefficient as deter- mined using the fragment method, .sigma. is the sum of the Hammet parameters for the R6 and R7 substituents, .sigma.I is the sum of the Inductive parameters for the R3 and R2 substituents.

Affiliated with

Also associated with

Rating

Method of suppressing appetite by administration of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of suppressing appetite by administration of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of suppressing appetite by administration of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2038490