Method of treating muscle tension, muscle spasticity and...

Details Method of treating muscle tension, muscle spasticity and... Method of treating muscle tension, muscle spasticity and...

C - Chemistry, Metallurgy

07

D

167/208, 260/277

C07D 205/04 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 205/00 (2006.01) C07D 205/02 (2006.01) C07D 211/80 (2006.01) C07D 213/00 (2006.01) C07D 213/63 (2006.01) C07D 213/69 (2006.01) C07D 213/81 (2006.01) C07D 233/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1294274

METHOD OF TREATING MUSCLE TENSION, MUSCLE SPASTICITY AND ANXIETY WITH 3-ARYL- OXYAZETIDINECARBOXAMIDES ABSTRACT OF THE DISCLOSURE A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxyazetidinecarboxamides having the formula: Image wherein Z is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloalkylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, lower- alkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof when they are possible.

502877

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