Method of tumor regression with vegf inhibitors

Details Method of tumor regression with vegf inhibitors Method of tumor regression with vegf inhibitors

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2519875

Methods of regressing or inhibiting a tumor in a subject by administering an agent capable of blocking, inhibiting, or ameliorating vascular endothelial growth factor (VEGF)-mediated activity to a subject in need thereof such that the tumor is regressed or inhibited. The method of the invention results in a reduction of tumor size and inhibition of tumor metastases. This method is particularly useful for patients suffering from bulky, metastatic cancers.

L'invention concerne des méthodes de régression ou d'inhibition d'une tumeur chez un sujet par le biais de l'administration d'un agent capable de bloquer, d'inhiber ou d'améliorer l'activité de médiation du facteur de croissance de l'endothélium vasculaire (VEGF) chez un sujet le nécessitant, de telle manière que la tumeur régresse ou est inhibée. Ladite méthode de cette invention débouche sur une diminution de la taille de la tumeur ou sur l'inhibition des métastases tumorales, et elle est particulièrement utilisée avec des patients souffrant de cancers métastatiques, volumineux.

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