Methods and apparatuses for stretching polymers

G - Physics – 01 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

G01N 1/28 (2006.01) B01F 5/06 (2006.01) B01L 3/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/44 (2006.01)

Patent

CA 2381361

The present invention provides structures and methods that allow polymers of any length, including nucleic acids containing entire genomes, to be stretched into a long, linear conformation for further analysis. The present invention also provides structures and methods for selecting and stretching polymers based on their lengths. Polymers are loaded into a device and run through the structures. Stretching is achieved by, e.g., applying shear forces as the polymer passes through the structures, placing obstacles in the path of the polymer, or a combination thereof. Since multiple molecules may be stretched in succession, extremely high throughput screening, e.g., screening of more than one molecule per second, is achieved.

La présente invention concerne des structures et des procédés permettant à des polymères longueurs de quelconques, y compris des acides nucléiques contenant des génomes entiers, d'être étirés dans une configuration cylindrique, linéaire pour des analyses supplémentaires. La présente invention concerne également des structures et des procédés de sélection et d'étirage de polymères en fonction de leurs longueurs. Les polymères sont chargés dans un dispositif et circulent à travers les structures. L'étirage est, par exemple, achevé par des forces de cisaillement lorsque le polymère passe à travers les structures ou une combinaison de celles-ci, en plaçant des obstacles dans le chemin du polymère. Etant donné que de multiples molécules peuvent être étirées successivement, des capacités de criblage extrêmement hautes, à savoir le criblage de plus d'une molécule par seconde est achevé.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Methods and apparatuses for stretching polymers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and apparatuses for stretching polymers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatuses for stretching polymers will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1734396

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.