A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/08 (2006.01) A61K 38/06 (2006.01)
Patent
CA 2601653
The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds.
L'invention porte sur des agents isolés de structures chimiques nouvelles présentant une activité chimique renforcée en tant que dérépresseurs de caspases inhibées par l'IAP. L'invention porte également sur une méthode de dérépression de caspases inhibées par l'IAP, et sur des méthodes de bioessais utilisant les composés marqués de l'invention et spécialement des composés marqués fluorescents.
Houghten Richard A.
Nefzi Adel
Ostresh John M.
Pinilla Clemencia
Reed John C.
Smart & Biggar
The Burnham Institute
Torrey Pines Institute For Molecular Studies
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