Methods and compositions for derepression of iap-inhibited...

A - Human Necessities – 61 – K

Patent

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Details

IPC codes

A61K 38/08 (2006.01) A61K 38/06 (2006.01)

Type

Patent

Patent number

CA 2601653

Description

The invention provides isolated agents having novel chemical structures and possessing superior activity as derepressors of IAP inhibited caspase. The invention further provides a method of derepressing an IAP-inhibited caspase. The invention further provides assay methods employing labeled compounds of the invention, especially fluorescent labeled compounds.

L'invention porte sur des agents isolés de structures chimiques nouvelles présentant une activité chimique renforcée en tant que dérépresseurs de caspases inhibées par l'IAP. L'invention porte également sur une méthode de dérépression de caspases inhibées par l'IAP, et sur des méthodes de bioessais utilisant les composés marqués de l'invention et spécialement des composés marqués fluorescents.

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