Methods and compositions for increasing gene expression

Details Methods and compositions for increasing gene expression Methods and compositions for increasing gene expression

A - Human Necessities

61

K

A61K 31/7105 (2006.01) A61P 35/00 (2006.01) C12N 15/85 (2006.01) C12N 15/113 (2010.01) A61K 48/00 (2006.01)

Patent

CA 2710953

The present invention provides compositions, pharmaceutical preparations, kits and methods for increasing ex-pression of a gene product in a cell by contacting the cell with a microRNA (miRNA) molecule comprising a ribonucleic strand that is complementary to a non-coding nucleic acid sequence of the gene.

La présente invention concerne des compositions, des préparations pharmaceutiques, des kits et des procédés pour augmenter l'expression d'un produit génique dans une cellule par la mise en contact de la cellule avec une molécule de microARN (miARN) comprenant un brin ribonucléique qui est complémentaire d'une séquence d'acide nucléique non codante du gène.

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