Methods and compositions relating to electrical detection of...

C - Chemistry – Metallurgy – 12 – Q

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12Q 1/68 (2006.01) G01N 27/00 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2393733

This invention relates to the detection of molecular interactions between biological molecules. Specifically, the invention relates to electrical detection of interactions such as hybridization between nucleic acids or peptide antigen-antibody interactions using arrays of peptides or oligonucleotides. In particular, the invention relates to an apparatus and methods for detecting nucleic acid hybridization or peptide binding using electronic methods including AC impedance. In some embodiments, no electrochemical or other label moieties are used. In others, electrochemically active labels are used to detect reactions on hydrogel arrays, including genotyping reactions such as the single base extension reaction.

L'invention se rapporte à la détection d'interactions moléculaires entre les molécules biologiques. Elle concerne plus particulièrement la détection électrique d'interactions telles que l'hybridation entre différents acides nucléiques ou d'interaction antigène - anticorps de peptides utilisant des réseaux de peptides et d'oligonucléotides. Elle concerne un appareil et des procédés pour détecter la liaison de peptides ou l'hybridation d'acides nucléiques au moyen de procédés électriques, y compris l'impédance du c.a. Dans certains modes de réalisation, on n'utilise aucun groupe fonctionnel électrochimique ou autre groupe fonctionnel d'étiquetage. Dans d'autres, on utilise des étiquettes à activité électrochimique pour détecter des réactions sur des réseaux d'hydrogel, y compris des réactions de génotypage telles que la réaction d'extension de base unique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Methods and compositions relating to electrical detection of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and compositions relating to electrical detection of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions relating to electrical detection of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1561514

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.