Methods and compositions utilizing quinazolinones

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/91 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) C07D 239/90 (2006.01)

Patent

CA 2413426

Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.

L'invention concerne des quinazolinones de formules (a, b, c et d). On utilise ces quinazolinones dans le traitement de maladies cellulaires proliferatives et de troubles liés à l'activité de la kinésine KSP .

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