Methods and devices for single-molecule whole genome analysis

Details Methods and devices for single-molecule whole genome analysis Methods and devices for single-molecule whole genome analysis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2729159

Provided are methods and devices for single-molecule genomic analysis. In one embodiment, the methods entail processing a double-stranded nucleic acid and characterizing said nucleic acid. These methods are useful in, e.g., determining structural variations and copy number variations between individuals.

La présente invention concerne des procédés et dispositif destinés à l'analyse génomique mono-moléculaire. Dans un mode de réalisation, ces procédés impliquent le traitement d'un acide nucléique bicaténaire et à caractériser ledit acide nucléique. Ces procédés permettent, par exemple, de déterminer les variations structurelles et les variations du nombre de copies d'un individu à l'autre.

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